D is correct because patients with HIV are more sensitive to extrapyramidal side effects (EPS) from antipsychotic medication use when compared to the general population. This was demonstrated in a small study (N=13) of men with new onset psychosis, where all 8 men receiving haloperidol developed EPS requiring benzotropine despite a mean daily dose of only 2.9mg haloperidol. Larger studies are not available.

Publication reference : Neuroleptic treatment of HIV-associated psychosis. HNRC group. Sewell DD, Jeste DV, McAdams LA et al. Neuropsychopharmacology. 1994 Jul;10(4);223-9.
Reference URL: https://www.nature.com/articles/npp199425.pdf