Which of the following statements is most accurate about lithium use in patients with renal disease?
Lithium is almost entirely excreted by the kidneys. It is contraindicated in patients with acute renal failure (Correct choice-C). A is incorrect because lithium may be conservatively dosed in patients with stable renal insufficiency, with frequent monitoring of levels. D is incorrect because lithium is completely dialyzed and therefore should be given as a single oral dose (300–600mg) following hemodialysis treatment. B is incorrect as lithium levels should not be checked until at least 2–3 hours after dialysis because re-equilibration from tissue stores occurs in the immediate postdialysis period. E is incorrect because lithium is removed by dialysis.
Publication reference : Textbook of Psychosomatic Medicine and C-L Psychiatry, Third Edition. Chapter 20 Renal Disease p582