Antiphospholipid antibodies, high disease activity, and absence of cutaneous manifestations such as malar rash and photosensitivity were correlated with psychosis in a cohort of 520 SLE patients (of whom 17% had psychosis). Hypoalbuminemia may increase the risk of steroid-associated psychosis by increasing free fraction of steroid, but not of SLE-related psychosis.

Publication reference : Appenzeller S, Cendes F, Costallat LT. Acute psychosis in systemic lupus erythematosus.Rheumatol Int. 2008 Jan;28(3):237-43.
Reference URL: https://www.ncbi.nlm.nih.gov/pubmed/17634902